The cinematic journey begins with an emotional monologue from Lucy, portrayed by Missi Pyle, as she candidly discusses her struggles as an overweight individual surrounded by slender peers during her college years. Her heartfelt sorrow is further intensified by a desperate phone call to her friend Becky, played by Melissa McCarthy, urging her to gather their friends for one last farewell trip to visit Lucy at Holland Lake Lodge in Condon, Montana, where she has taken charge of this quaint establishment.

Under Becky’s coordination, the group gathers at an airport in the breathtaking Big Sky Country. This reunion features a diverse ensemble, including Becky’s husband Richard, with notable characters such as commodities trader George, Grammy-nominated rap producer Trevor, flight attendant Austin, and State Representative Raye, who brings along his wife Mary, characterized by the talents of Octavia Spencer. Upon their arrival at the lodge, a stunning blonde woman greets them, prompting Lucy to unveil a shocking transformation that has rendered her almost unrecognizable from her past self.

During a casual lunch, Lucy opens up about her recent gastric bypass surgery and shares that she is just a few pounds away from her desired weight. The very next morning, excitement stirs as Lucy makes an unexpected announcement about a four-day hiking adventure, aimed at shedding her final pounds. The film unfolds against the stunning backdrop of Montana, gradually peeling back the layers of Lucy’s friends as their personal battles and insecurities come to light.

A monumental revelation from George about his sexual orientation serves as a turning point, encouraging others in the group to confront their hidden issues. The unraveling of Raye and Mary’s unhappy marriage leads Mary to remove her wedding ring and break away from Raye. Simultaneously, Becky’s hidden struggles within her marriage to Richard come to the forefront, revealing an affair with a coworker. As the hiking escapade approaches its conclusion, Lucy prepares dinner for her friends while waiting for Sam to take them back to the reality of their lives.

Tension rises among the group as they get ready to part ways, with Becky channeling her frustration primarily at Lucy for orchestrating this reunion under false pretenses. In a heartfelt moment of vulnerability, Lucy admits that she believed attaining a slimmer physique would grant her the happiness her friends seemingly enjoyed. However, this journey unfolds to reveal that none of them are truly satisfied, highlighting that weight loss is merely a superficial aspect of their existence.

As the group frantically speeds back to the lodge amidst rising chaos, tragedy strikes when Sam suffers a sudden heart attack, sending their vehicle crashing off the road and claiming his life instantly. The calamity deepens with Richard’s own passing as he collapses while awaiting medical aid, leaving behind a final heartfelt apology to Becky for his past mistakes. In the wake of this tragedy, the surviving friends, worn yet appreciative, are left to confront the profound weight of their loss.

In the midst of the turmoil, Raye takes charge, racing off to find help, thus dispelling Mary’s doubts about his ability to act selflessly. His determination pays off as he returns to Washington, achieving a coveted Senate seat.

As the dust settles from this tumultuous chapter, the survivors come together for a moment of healing, finding solace in their shared experiences. The serene beach, bathed in sunlight, provides a peaceful setting for their collective catharsis. Lucy and Becky, with Becky carrying Richard’s legacy as she is now pregnant, wade into the waves to scatter Richard’s ashes, a poignant tribute to a life they cherished. In the end, it is not the chaos that defines them, but the unbreakable bonds of friendship forged through adversity, as they embrace with intertwined grief and gratitude, symbolizing the tender growth of new beginnings.