Evelyn Quan Wang, portrayed by Michelle Yeoh, is a middle-aged Chinese American immigrant who operates a laundromat alongside her husband, Waymond. Their journey began two decades ago when they eloped to the United States and welcomed their daughter, Joy. Today, Evelyn faces a challenging ordeal as their laundromat is under scrutiny from the Internal Revenue Service (IRS). Adding to her troubles, Waymond is trying to get her attention by serving her divorce papers as a means to discuss their faltering marriage, all the while dealing with her stern father, Gong Gong, who has come to visit for the Chinese New Year celebrations. Compounding the family drama, Joy is grappling with depression and a strained relationship with Evelyn, particularly regarding Joy’s non-Chinese girlfriend, Becky.

During a tense meeting with IRS inspector Deirdre Beaubeirdre, the situation escalates dramatically when Waymond’s body is overtaken by Alpha-Waymond, a version of himself from the enigmatic “Alphaverse.” He reveals to Evelyn the existence of countless parallel universes, wherein every choice creates a different reality. A formidable threat looms in the form of Jobu Tupaki, the splintered mind of Alpha-Joy, who can manipulate the multiverse after a series of intensive verse-jumps. Jobu has constructed a chaotic black hole-like “everything bagel” that threatens to unravel reality.

To confront this impending doom, Alpha-Evelyn—a version of herself from the Alphaverse—tasked them with finding a way to defeat Jobu Tupaki. As Evelyn begins her journey into another universe, her physical body remains present, but her mind is elsewhere during the fraught IRS meeting where Deirdre accuses her of fraudulent activities. In a moment of confusion, Evelyn reacts by striking Deirdre, leading to a call for security. Thankfully, Alpha-Waymond reappears to aid Evelyn’s escape.

However, they find themselves cornered in the IRS building as Alpha-Dierdre materializes, blocking their way. Alpha-Waymond grants Evelyn the ability to verse-jump, jumpstarting her fight against Jobu’s minions converging on the IRS. Through her jumps, Evelyn discovers alternate versions of herself, including one where she is a Kung Fu master and celebrated film star. She begins to confront the reality of Waymond’s intentions regarding the divorce.

As Evelyn harnesses her new powers to defeat Alpha-Dierdre and the minions, Jobu becomes aware of Evelyn’s growing strength. Meanwhile, Gong Gong is possessed by Alpha-Gong Gong, who urges Evelyn to eliminate Joy to thwart Jobu’s plans. Rejecting this notion, Evelyn resolves to face Jobu by embracing her newfound abilities through continued verse-jumping, believing that the best way to defeat Jobu is to adopt her perspective.

The confrontation escalates when Jobu kills Alpha-Waymond, and she reveals to Evelyn her nihilistic worldview: that nothing matters. As Evelyn wrestles with her splintered mind during an intense sequence of verse-jumping across bizarre worlds, Jobu confesses her true aim—finding an Evelyn who understands nothing matters, all while eliminating those who dissent.

In a pivotal moment, at the brink of entering the everything bagel, Evelyn pauses, reflecting on Waymond’s heartfelt pleas for kindness and empathy amidst chaos. Reconnecting with Waymond, she embraces Joy and acknowledges her relationship with Becky, finally addressing Gong Gong in acknowledging their love. Following this revelation, Evelyn gains clarity and decides to combat Jobu not with hostility, but with compassion.

As they strive to rescue Jobu from the bagel, Evelyn expresses unwavering devotion to Joy, affirming that even in a tumultuous multiverse, she would choose Joy every single time. The emotional climax leads to a touching reconciliation as the family’s dynamics begin to mend.

Eventually, with their relationships flourishing, they return to the IRS to amend their taxes. As the meeting unfolds, Evelyn’s gaze wanders briefly to her alternate selves, only for her to ground herself back in her original universe, now with a renewed sense of purpose and connection.