As the oppressive heat of the summer of 2005 wanes in New Orleans, Daisy Fuller finds her vitality slipping away within the sterile confines of a hospital. Summoned to her bedside, her daughter Caroline begins to narrate a touching story about the blind clockmaker Mr. Gateau, who crafted a remarkable timepiece for a train station back in 1918. This one-of-a-kind clock, which defies the natural rhythm of time, serves as an emotional memorial for those who have suffered loss due to the Great War—a poignant reflection of Mr. Gateau’s own heartache. Daisy urges Caroline to delve into the pages of Benjamin Button’s diary, setting the stage for a remarkable journey through the dimensions of time and existence.

On the fateful evening of November 11, 1918, a child enters the world, albeit with the frailty of an old man. Following the death of his mother, Caroline, shortly after childbirth, his father, Thomas Button, a prosperous manufacturer, abandons him at a nursing home’s doorstep. Fortunately, the warm-hearted caretaker, Queenie, and the gentle kitchen staffer, Mr. Weathers, discover the infant, deciding to raise him as their own and naming him Benjamin. As the years pass, Benjamin undergoes a mesmerizing transformation, aligning himself with the elderly residents around him, even as his mind retains childlike innocence. His unique condition allows him to age backward, transitioning from a wheelchair to crutches, and eventually embracing the ability to walk freely.

The pivotal moment arrives on Thanksgiving Day in 1930, when Benjamin encounters the bright and spirited Daisy Fuller, a seven-year-old girl whose grandmother resides in the nursing home. Their initial meeting is nothing short of enchanting, igniting a deep connection between two souls destined to cross paths throughout their lives. Later, he secures a position aboard the tugboat Chelsea, under the experienced helm of Mike Clark. As fate would have it, Thomas Button reappears in Benjamin’s life, enshrouded in mystery.

By Autumn 1936, Benjamin embarks on an adventurous journey across the globe with the tugboat crew, sending heartfelt postcards to Daisy as she begins to flourish in the bustling streets of New York City. However, the world is engulfed in war, and Benjamin finds himself smitten by Elizabeth Abbott, the captivating wife of the British trade minister in Murmansk. Their romance, however, fails to withstand the trials of life, leaving Benjamin heartbroken and solitary.

With the onset of December 1941 and World War II, the Chelsea is called to salvage operations, where Mike Clark volunteers the vessel for the U.S. Navy. In a harrowing turn of events, they discover a sunken U.S. transport brimming with deceased American soldiers. A German U-boat emerges and attacks their tugboat, prompting Captain Mike to bravely ram the submarine to safeguard his crew. This explosive confrontation claims the lives of many aboard, sparing only Benjamin and Rick Brody, who are eventually rescued.

As May 1945 unfolds, Benjamin returns to the city that holds a permanent place in his heart, reuniting with Queenie, who reveals Mr. Weathers’ demise. He reconnects with a now-grown Daisy, who harbors her own dreams and ambitions. Yet, Benjamin’s heart remains steadfastly loyal, unable to fully embrace her overtures as she leaves once more. Meanwhile, the ailing Thomas Button awaits Benjamin’s return, unveiling the obscured truths surrounding Benjamin’s birth and lineage. On his deathbed, Thomas bequeaths his button manufacturing business and estate to Benjamin, paving the way for a new chapter in his enigmatic life.

In 1947, Benjamin unexpectedly appears at Daisy’s New York doorstep but leaves when he realizes she is involved with someone else. A decade later, Daisy’s dancing career faces a harsh interruption; a catastrophic car accident in Paris leaves her leg severely injured. When Benjamin visits her again, she is struck by his unaltered looks, yet her frustration with her physical state leads her to demand that he stay out of her life.

As time passes, Daisy finds her way back to New Orleans, where the two reconnect. Now that they are at a similar stage in life, their relationship flourishes into profound love. The passing of Queenie signifies the onset of a new era for the pair, culminating in 1967 when Daisy announces her pregnancy and gives birth to their daughter, Caroline, in spring of 1968.

As Benjamin continues to age in reverse, uncertainties loom over his ability to be a responsible father. Resolute, he liquidates his assets, ensuring a secure future for Daisy and Caroline before setting off on a solitary journey through the 1970s. When he emerges in 1980, having physically transitioned into a young man, Benjamin is introduced to Daisy by her husband Robert as a family friend. A private reunion at his hotel room soon follows, stirring bittersweet emotions.

Years roll on, and Daisy finds herself a widow once again. Yet, in 1990, social workers uncover Benjamin, now a pre-teen exhibiting signs of dementia, ultimately compelling her to care for him. As Benjamin’s condition deteriorates, Daisy commits herself to nurturing him, even moving into the nursing home in 1997, as he regresses further back into infancy.

As the years slip away, the once-majestic clock crafted by Gateau is replaced by a sleek modern digital timer in 2002. Sadly, Benjamin passes away in Daisy’s arms in 2003, appearing as an infant yet holding the memory of over 84 years. In 2005, Daisy shares with Caroline that Benjamin is indeed her father before confronting her own imminent mortality. The storied chamber housing Gateau’s clock is ultimately inundated by the waters of Hurricane Katrina, yet the clock stubbornly continues to tick backward—a haunting yet beautiful emblem of the unpredictable passage of time itself.