Willie Morris reflects on his childhood during the early 1940s, a time profoundly influenced by his cherished companion, a Jack Russell Terrier named Skip. As a lonely boy, Willie navigates life with a gruff yet proud father, a Spanish Civil War veteran, and a vibrant, chatty mother who is a devoted housewife. Being an only child and small for his age, he has limited friendships. His closest ally is Dink Jenkins, the local sports star in Mississippi, who unexpectedly faces deployment. In a bid to provide Willie with companionship, his mother makes the bold decision to bring home a dog, despite his father’s objections.

With time, the bond between Willie and Skip blossoms into a steadfast friendship. However, life at school is challenging for Willie, with bullies like Big Boy Wilkinson, Henjie Henick, and Spit McGee making his days miserable. In a turning point, Dink sends Willie a German helmet and belt from the front lines, which becomes the catalyst for the bullies. They coerce Willie into playing a game to reclaim his belongings, with Skip loyally jumping to his defense. The plot thickens when the boys trick Willie into a night spent in a graveyard, claiming it’s haunted. To prove his courage, Willie faces this challenge under the looming threat of losing his prized helmet.

Throughout the night, danger appears in the form of two moonshiners, Millard and Junior, and as they prepare their illicit goods, a commotion ensues. Skip bravely jumps at the moonshiners, leading to a confrontation where Willie must choose between his safety or that of his loyal dog. After an harrowing encounter, the other boys accept him into their gang, marking a turning point in Willie’s social life.

With Skip beside him, Willie’s boyhood is filled with new friends and even a girlfriend, Rivers. However, their friendship faces turbulence when Dink returns home from the war, struggling with the psychological scars and drinking issues that come from his experiences. The pressure mounts for Willie during his first ball game, where he feels ashamed of his performance, and in a moment of frustration, he strikes Skip, causing a rift between them. Disheartened, Skip runs away, leaving Willie alone.

In a dramatic turn of events, Skip inadvertently finds himself trapped in a crypt while Willie searches for him. When Willie hears Skip’s barks and rushes to his aid, the situation escalates dangerously. Dink arrives just in time to confront the moonshiners, saving Skip from grave peril. In a heartbreaking moment, as Willie’s loved ones gather in concern, Skip nears death but miraculously revives, showering Willie with affection.

Willie’s deep connection with Skip symbolizes his own struggles with loneliness and the joys of friendship. As he prepares to venture to Oxford University, Willie must say goodbye to Skip, who has become a part of his life. After Willie’s departure, Skip remains with his parents, ultimately passing away on Willie’s bed. As a final tribute, Skip is laid to rest under the beloved elm tree, a testament to their unbreakable bond and the lessons learned throughout their time together.